International differences: selection, noise, or real?

Are international differences in the outcomes of acute coronary syndromes apparent or real? A multilevel analysis.

STUDY OBJECTIVE International variation in the outcomes of patients with acute coronary syndromes (ACS) has been well reported. The relative contributions of patient, hospital, and country level factors on clinical outcomes, however, remain unclear, and thus, was the objective of this study. DESIGN Multilevel logistic regression models were developed for death/(re)infarction (MI) at 30 days a...

Gender differences in epilepsy : perceived or real ?

Epilepsy is the third most common chronic neurological condition across all ages, affecting around 1% of the population world wide. While epidemiological studies do not indicate any differences in the incidence of epilepsy in males and females, there may be significant differences in the impact and effect the condition may have between males and females across all ages. These differences may no...

Sex Differences in Distress: Real or Artifact?

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Racial differences in coronary vasomotor response or selection bias?

Response or Selection Bias? To the Editor: Pristipino et al1 found that, compared with white patients in Italy, Japanese patients with myocardial infarction had a 3-fold-greater incidence of coronary spasm and a vasoconstrictive response to acetylcholine. The authors conclude that these “major racial differences in the coronary constrictor response{warrant further investigations because they ma...

Real or apparent ethnic differences in cellular adhesion molecule activity?